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961.
Jun Lin Wei-ying Zheng Peng-ruo-feng Liu Ning Zhang Hui-ping Lin Yi-jing Fan Xin-hua Gu Oliver Vollrath Christian Mehl 《Journal of Zhejiang University. Science. B》2014,15(7):649-660
The aim of this study is to evaluate the influence of Tooth Mousse (TM) application, smear layer removal, and storage time on resin-dentin microtensile bond strength (μTBS). Dentin specimens were divided into two groups: (1) smear layer covered; (2) smear layer removed using 15% EDTA for 90 s. In each group, half the specimens were treated once with TM for 60 min. After bonding procedures using a two-step self-etching adhesive (Clearfil SE Bond (CSE); Kuraray Medical, Tokyo, Japan), an all-in-one adhesive (G-Bond (GB); GC Corp, Tokyo, Japan), and a total-etch adhesive (Adper Single Bond 2 (SB); 3M ESPE, St. Paul, MN, USA), the specimens were stored for 3 d or 6 months in deionized water at 37 °C, and μTBS was tested and analyzed. With the exception of SB (no TM application) and GB, the μTBS was significantly increased for CSE and SB using EDTA pre-conditioning and 3 d of storage (P≤0.001). Bond strength of GB decreased significantly when using EDTA (3 d storage, P<0.05). TM application only increased the μTBS of GB (no EDTA) and SB (with EDTA) after 3 d (P≤0.02). Comparing the adhesives after 3 d of storage, CSE exhibited the greatest μTBS values followed by GB and SB (P≤0.02). The factors of adhesive, EDTA, and TM did not show any significant impact on μTBS when specimens were stored for 6 months (P>0.05). The additional application of TM and EDTA for cavity preparation seems only to have a short-term effect, and no influence on μTBS of dentin bonds after a period of 6 months. 相似文献
962.
文章阐述和分析了国内美术院校科研管理中存在的问题及成因,并对提升美术院校科研管理水平提出了对策建议,同时,就高校美术专业科研管理评价体系的建设与实践做了介绍。 相似文献
963.
Jun-xian CAO Lu FU Qian-ping GAO Rong-sheng XIE Fan QU 《Journal of Zhejiang University. Science. B》2014,15(6):515-521
Objective
To investigate stretch-induced electrophysiological changes in chronically infarcted hearts and the effect of streptomycin (SM) on these changes in vivo.Methods
Sixty Wistar rats were divided randomly into four groups: a control group (n=15), an SM group (n=15), a myocardial infarction (MI) group (n=15), and an MI+SM group (n=15). Chronic MI was obtained by ligating the left anterior descending branch (LAD) of rat hearts for eight weeks. The in vivo blockade of stretch-activated ion channels (SACs) was achieved by intramuscular injection of SM (180 mg/(kg·d)) for seven days after operation. The hearts were stretched for 5 s by occlusion of the aortic arch. Suction electrodes were placed on the anterior wall of left ventricle to record the monophasic action potential (MAP). The effect of stretching was examined by assessing the 90% monophasic action potential duration (MAPD90), premature ventricular beats (PVBs), and ventricular tachycardia (VT).Results
The MAPD90 decreased during stretching in both the control (from (50.27±5.61) ms to (46.27±4.51) ms, P<0.05) and MI groups (from (65.47±6.38) ms to (57.47±5.76 ms), P<0.01). SM inhibited the decrease in MAPD90 during inflation ((46.27±4.51) ms vs. (49.53±3.52) ms, P<0.05 in normal hearts; (57.47±5.76) ms vs. (61.87±5.33) ms, P<0.05 in MI hearts). The occurrence of PVBs and VT in the MI group increased compared with that in the control group (PVB: 7.93±1.66 vs. 1.80±0.86, P<0.01; VT: 7 vs. 1, P<0.05). SM decreased the occurrence of PVBs in both normal and MI hearts (0.93±0.59 vs. 1.80±0.86 in normal hearts, P<0.05; 5.40±1.18 vs. 7.93±1.66 in MI hearts, P<0.01).Conclusions
Stretch-induced MAPD90 changes and arrhythmias were observed in chronically infarcted myocardium. The use of SM in vivo decreased the incidence of PVBs but not of VT. This suggests that SACs may be involved in mechanoelectric feedback (MEF), but that there might be other mechanisms involved in causing VT in chronic MI. 相似文献964.
You-qun HUANG Rong GOU Yong-shu DIAO Qing-hua YIN Wen-xing FAN Ya-ping LIANG Yi CHEN Min WU Li ZANG Ling LI Jing ZANG Lu CHENG Ping FU Fang LIU 《Journal of Zhejiang University. Science. B》2014,(1)
研究目的:探讨Charlson合并症指数(CCI)对2型糖尿病肾病死亡率的预测作用。研究方法:建立2型糖尿病肾病研究队列,根据CCI评分将患者合并症的严重程度分为三度:轻度(CCI1–2分)、中度(CCI 3–4分)、重度(CCI≥5分)。将影响死亡率的因素及按CCI分层后的组间差异指标进行Logistic回归分析及方差分析(ANOVA)。Kaplan-Meier生存曲线分析CCI指数对生存时间及死亡率的影响。重要结论:533例2型糖尿病肾病患者纳入研究。所有患者的CCI评分均大于1,44.7%(238/533)的患者死亡。患者的死亡率随CCI评分增加而增加,CCI 1–2分患者的死亡率为21.0%(50/238),CCI 3–4分患者的死亡率为56.7%(135/238),CCI≥5分患者的死亡率为22.3%(53/238)。Logistic回归分析显示CCI评分、血红蛋白和血浆白蛋白水平是患者死亡率的预测因子(P0.05)。方差分析结果显示,与CCI评分相对较低的患者相比,CCI评分越高的患者其血红蛋白水平较低,而血清肌酐较高,死亡率也更高。Kaplan-Meier生存曲线显示CCI评分越高的患者生存时间越短。CCI评分是一种简单易行且实用的评估疾病合并症的方法,可用于预测2型糖尿病肾病患者的死亡率。关注2型糖尿病肾病患者的合并症将有利于早期、有效治疗及改善预后。 相似文献
965.
辅助生殖技术学龄前单双胎子代的认知发展存在差异么?(英文)简 总被引:1,自引:0,他引:1
Lan-feng XING Yu-li QIAN Lu-ting CHEN Fan-hong ZHANG Xin-fen XU Fan QU Yi-min ZHU 《Journal of Zhejiang University. Science. B》2014,15(1):51-57
Objective: To explore whether there exist differences in cognitive development between singletons and twins born after in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). Methods: A total of 566 children were recruited for the study, including 388 children (singletons, n=175; twins, n=213) born after IVF and 178 children (singletons, n=87; twins, n=91 ) born after ICSI. The cognitive development was assessed using the Chinese-Wechsler Intelligence Scale for Children (C-WISC). Results: For all pre-term offspring, all the intelligence quotient (IQ) items between singletons and twins showed no significant differences no matter if they were born after IVF or ICSI. There was a significant difference in the cognitive development of IVF-conceived full-term singletons and twins. The twins born after IVF obtained significantly lower scores than the singletons in verbal IQ (containing information, picture & vocabulary, arithmetic, picture completion, comprehension, and language), performance IQ (containing maze, visual analysis, object assembly, and performance), and full scale IQ (P〈0.05). The cognitive development of full-term sin- gletons and twins born after ICSI did not show any significant differences. There was no significant difference between the parents of the singletons and twins in their characteristics where data were collected, including the age of the mothers, the current employment status, the educational backgrounds, and areas of residence. There were also no consistent differences in the duration of pregnancy, sex composition of the children, age, and height between sin- gletons and twins at the time of our study although there existed significant differences between the two groups in the sex composition of the full-term children born after ICSI (P〈0.05). Conclusions: Compared to the full-term singletons born after IVF, the full-term twins have lower cognitive development. The cognitive development of full-term singletons and twins born after ICSI did not show any significant differences. For all pre-term offspring, singletons and twins born after IVF or ICSI, the results of the cognitive development showed no significant differences. 相似文献
966.
考试出题是考试活动的重要内容之一。出题方式与内容的变化,直接反映着考试制度文化变迁,是评价与衡量考试制度质量的重要指标。清代科举制度历经悠久的发展历程,其出题方式及考试内容趋于完善与稳定,成为彰显科举文化与精神的重要内容,也是考察清代科举考试制度改革与调整的重要视角。 相似文献
967.
课程的选择和组织问题是教育中的一个关键性问题。着眼培养"能打仗,打胜仗"的高素质新型军事人才,院校课程改革,需要开阔视野,从深入比较中获得启示。本文选取MIT、TUM两所一流大学,从人才培养目标、课程体系及结构、课程及其教学特点等维度,进行一般剖析与综合比较。军队综合大学课程改革,应借鉴有益经验,从人才培养目标、教育模式、课程体系、课程内容和教学形式进行变革。 相似文献
968.
Jian SHEN Yu ZHU Hai YU Zuo-xu FAN Feng XIAO Pan WU Qi-hui ZHANG Xiao-xing XIONG Jian-wei PAN Ren-ya ZHAN 《Journal of Zhejiang University. Science. B》2014,(3)
研究目的:补阳还五汤对脑缺血后缺血区血管生成的影响及其机制。创新要点:研究结果表明补阳还五汤可能通过增加血管生成素-1的表达,促进缺血区血管新生,从而促进脑梗死后神经功能恢复。研究方法:通过神经功能评分、脑梗死及脑萎缩体积评估神经功能恢复情况;通过免疫组化及免疫印迹等方法检测血管密度及血管生成因子的表达情况。重要结论:补阳还五汤增加脑缺血后血管生成素-1的表达,能够促进脑梗死缺血区血管生成。 相似文献
969.
巴斯奈特的文化翻译理论认为翻译不是单纯的文字处理,而是文化内部以及文化之间的交流,翻译的对等就是原文与译文之间的文化功能的对等.以文化翻译理论为指导,笔者主张采用音译加注释、直译加注释、意译加注释、省略等翻译方法,翻译福建民俗文化,以期创出最佳译文,满足文化交流需要. 相似文献
970.
为了探讨商洛市不同区域(北部区域、中部区域、南部区域)野生地木耳中多糖含量、蛋白质含量的差异,采用水提醇沉法、凯氏定氮法分别对商洛市不同区域野生地木耳中多糖含量和蛋白质含量进行了测定,并选用石墨炉原子吸收光谱法和原子荧光光度法分别测定了样品中铜、铅以及砷的含量。结果表明:三个区域中,北部区域样品所含的多糖含量和蛋白质含量最高,分别占干重的5.89%和18.97%;原子吸收法测得南部区域样品和中部样品中铅、砷含量最低,分别为0.2678、0.6953 mg·kg-1。 相似文献